Wellsboro is a borough in Tioga County, Pennsylvania, United States, 52 miles northwest of Williamsport. Early in the 20th century, Wellsboro was the shipping point and trade center for a large area. It had fruit evaporators, flour and woolen mills, a milk-condensing plant, marble works, saw mills, foundry and machine shops, and manufactories of cut glass, chemicals, rugs, bolts, cigars, carriages, and furniture. In 1900, 2,945 people lived here; in 1910, 3,183 lived here. The population was 3,328 at the 2000 census. It is the county seat of Tioga County, and also home to the Grand Canyon of Pennsylvania.